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Propargyl-Acetyl-Val-Cit-PAB(m-PEG8)-MMAE fluorescent 401 Purity (HPLC) >= 95%

Propargyl-Acetyl-Val-Cit-PAB(m-PEG8)-MMAE fluorescent 401 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing

SKU: 35028954829 · From webdevsolutions.tech

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Description

401 Purity (HPLC) >= 95% Solubility DMSO

CA-Ac is a HaloTag ligand used as a small-sized label for comparison with other HaloTag ligands

Its fluorescence is relatively pH-insensitive

and a brief treatment with 100 mM MESNA results in a near-complete loss of fluorescence

Propargyl-Acetyl-Val-Cit-PAB(m-PEG8)-MMAE fluorescent 401 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing

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