Mal-Propionyl-PEG2-Val-Cit-PAB(m-PEG4)-PNP Size:100mg Product Name DOTA-PEG1-propargyl Synonyms CAS

Product Name DOTA-PEG1-propargyl Synonyms CAS Number n/a Related CAS Molecular Formula C21H35N5O8 Molecular Weight 485

261 SMILES FC(F)(F)C1=CC=C(C(=O)NC2=CC(=CC=C2)C2=NN=NN2)C(=O)N1 Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO

DMF Shipping Conditions Shipped on gel packs Storage Conditions Store at -20°C and protected from light Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCN)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Mal-Propionyl-PEG2-Val-Cit-PAB(m-PEG4)-PNP Size:100mg Product Name DOTA-PEG1-propargyl Synonyms CASSOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating