Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4) dacf1 Nature 588

Nature 588

NCCCCCCNC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name CC-220 Synonyms Iberdomide CAS Number 1323403-33-3 Related CAS Molecular Formula C25H27N3O5 Molecular Weight 449

COA          MSDS

Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4) dacf1 Nature 588SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Acetyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Acetyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. Derived from established