MaP555-DBCO (cell-permeable fluorogenic dye) Sulforhodamine B Kaltheuner

Kaltheuner

339 SMILES OCCCCOC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

328 SMILES OC(=O)C1=CC=CC(NC(=O)C2=C(OC3=CC=CC=C3)C=C(NC2=O)C(F)(F)F)=C1 Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO

and retains fluorescence in acidic conditions where fluorescein dims

MaP555-DBCO (cell-permeable fluorogenic dye) Sulforhodamine B KaltheunerMaP555 DBCO is is a fluorogenic probe. MaP555 is a small molecule fluorogenic probe with excellent cell permeability. It is converted from 6 carboxytetramethylrhodamine (6 TAMRA) and has similar spectroscopic properties of 6 TAMRA. MaP555 has an acyl sulfamide structure which favors the spirolactam form, thus has excellent cell permeability. When the probe binds to its cellular targets, MaP555 mainly exists in the fluorescent zwitterion form. The good