Propargyl-Acetyl-Val-Cit-PAB(m-PEG8)-PNP Size:10mg CCNC1=C(C)C=C2C(OC3=C\C(=[NH+]\CC)C(C)=CC3=C2C2=CC(=CC=C2C([O-])=O)C(O)=O)=C1 Purity (HPLC): ≥ 95%

CCNC1=C(C)C=C2C(OC3=C\C(=[NH+]\CC)C(C)=CC3=C2C2=CC(=CC=C2C([O-])=O)C(O)=O)=C1 Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

NCCC#CC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

NCCCNC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

British Journal of Pharmacology n/a

Propargyl-Acetyl-Val-Cit-PAB(m-PEG8)-PNP Size:10mg CCNC1=C(C)C=C2C(OC3=C\C(=[NH+]\CC)C(C)=CC3=C2C2=CC(=CC=C2C([O-])=O)C(O)=O)=C1 Purity (HPLC): ≥ 95%SOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating leaving group, enabling efficient and selective conjugation of the payload to the linker. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine