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In rodent models of nicotine exposure, doses have centered around 12 mg/kg per day, which was determined to be consistent with pregnant smokers consuming 20 cigarettes each day 29

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Additional symptoms of THC withdrawal can include things like: Anger, irritability and aggression Nervousness and anxiety Restlessness Decreased appetite or weight Depression Cravings or a strong urge to use again Sleep issues like insomnia, unsettling dreams or lack of quality sleep Tremors Headaches and sweating Abdominal pain or discomfort, nausea and vomiting Knowing what withdrawal symptoms look like and how they may be showing up for you can help you evaluate whether you are being affected by THC dependence