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George BJ, Schultz BD, Palma T, Vette AF, Whitaker DA, Williams RW (2011) An evaluation of EPAs National-Scale Air Toxics Assessment (NATA): Comparison with benzene measurements in Detroit, Michigan

Times per day (use lasting 10 minutes or 15 puffs) and puffs per day (actual number of puffs on the device) are not equivalent measures, unless the participant only takes, on average, just one puff every 10 minutes

This slower uptake, an independent study shows, may be why people trying to stop say the gum or lozenges dont relieve their craving like a cigarette does and why tobacco companies would like to punt the pouch as NRT while it actually just tricks users into reaching for a smoke