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Epigenetic silencing of p21 by long non-coding RNA HOTAIR is involved in the cell cycle disorder induced by cigarette smoke extract

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[4] [16] Additional risks include: Increased susceptibility to infections , particularly respiratory infections Poorer wound healing following surgery or injury Higher rates of erectile dysfunction in men Greater risk of developing diabetes-related complications at a younger age Urgent foot problems : If you develop a new foot ulcer, spreading infection, severe pain, colour change, or a cold foot, seek same-day assessment through your diabetes foot protection team or urgent care service, as recommended by NICE guidance