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How Long Does Nicotine Stay in Your System? MD Spiro Bro smoked a cigarette in 27 seconds, Fun fact (research based):, Some studies suggest that nicotine may be associated with a slightly lower risk of certain conditions, such as Parkinsons disease This equates to nearly 7 hours of life lost when smoking an average pack of 20 cigarettes." It Doesn't Take Much Smoking to Kill You, Study Finds
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