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In a mouse model of ovalbumin (OVA)-induced asthma, the researchers found that formaldehyde in e-cigarettes activated the TRPV4-p38 MAPK pathway, further aggravating airway hyperreactivity [70]

Conversely, psoriasis risk was higher for current smokers than never smokers

Yet, we still see that tobacco use is responsible for an estimated 2.5 million deaths annually and that tobacco use among youths is alarmingly high

doi: 10.3389/fcimb.2022.841465 Received 22 December 2021 Accepted 02 March 2022 Published 31 March 2022 Volume 12 - 2022 Edited by Nar Singh Chauhan, Maharshi Dayanand University, India Reviewed by Huajun Zheng, Shanghai Institute for Biomedical and Pharmaceutical Technologies, China