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Over time, this plaque hardens and narrows the arteries, limiting the flow of oxygen-rich blood to ones organs and other parts of the body

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Similarly, mice exposed to EC vapor increased human rhinovirus loads ( EC use is reported to cause COPD-like illnesses ( EC use was attributed to epithelial barrier damage in capillary endothelial cells and lung epithelial cells ( The production of ROS by EC, paired with the reduction of cellular glutathione levels, suggests that dual users may be subjected to higher levels of oxidative stress than single-substance users

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