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bioRxiv 2018

You may have ongoing coughing with colored mucus, and your lungs may more easily pick up infections

Tobacco smoking affects the serum levels of many coadministered drugs due to induction of cytochrome P450 (CYP) hepatic enzymes (especially CYP1A2) by polycyclic aromatic hydrocarbons and non-nicotinic chemical constituents, resulting in more rapid metabolism and clearance of certain drugs

Ninety-one percent had previously attempted to quit but failed, and the majority had previously tried smoking cessation medications or behavioral therapy without success