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In contrast, other cells of the body suffered only indirect damage, as tobacco smoking seems to affect key mechanisms in these cells that in turn mutate DNA. The study revealed at least five distinct processes of DNA damage due to cigarette smoking

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Some harmful substances that lead to oral cancer are: Toxins Carcinogens Nicotine Financial Impact of Smoking-Related Diseases Smoking-related cancers often require extensive medical care, including chemotherapy, radiation therapy, surgery, and long-term medications

Smokers are more likely to develop type 2 diabetes, as well as related complications like kidney disease, vision problems and nerve or circulation damage that can result in amputation