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"Whereas some experts welcome ENDS as a pathway to the reduction of tobacco smoking, others characterize them as products that could undermine efforts to denormalize tobacco use," the WHO stated, adding that e-cigarettes "represent an evolving frontier, filled with promise and threat for tobacco control."In mid-April, the Centers for Disease Control and Prevention reported a startling statistic: in just a single year, the use of electronic cigarettes among middle and high school students more than tripled

This would allow us to determine long term changes in biomarkers of potential harm exclusively due to vaping and not as a consequence of prior longterm smoking. This tells us that even with all the evidence available to-date, the fact that almost all vapers featured in studies used to be smokers means experts cannot be certain anything negative they find may not just be a consequence of their habits before making the switch

Omorou, Marie-Pierre Sylvestre, Jennifer Brunet, Jennifer O'Loughlin Journal of Adolescent Health 23

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