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Routine laboratory investigations: Complete blood count (CBC) was performed using the automated haematology analyser Sysmex KX 21N (Kobe, Japan), and biochemical analyses using the Cobas c311 system (Roche Diagnostics, Mannheim, Germany) for kidney, liver function parameters and microalbumin in urine (using 24 hours urine)

The risks of cardiovascular disease and lung disease have not been quantified for e-cigarettes, but are also likely to be substantially less than those from smoking 42

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