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Constantly Evolving Landscape It will be important to understand how these findings translate from the controlled setting of a clinical trial to the real world where people use e-cigarettes in various ways, including without behavioral support for cessation, and for reasons other than quitting smoking, Dr

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In studies, effects have included increased arterial stiffness, impaired endothelial function, changes in heart regulation, increased blood pressure, peripheral vasoconstriction and possible disruption of the vascular barrier in the brain

The findings suggest that regulatory changes influence the focus of online communities, but more data are needed to fully understand the implications for public health and safety.