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Both NNK and NNAL are metabolized into intermediates which bind to human lung DNA, transform human epithelium in vitro , and induce non-tumorigenic human bronchial epithelial cells to become neoplastically transformed in nude mice after subcutaneous transplantation [21]

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Retrieved 8 June 2008

9 CAGW argued that the proposed rule to ban menthol flavoring in cigarettes would negatively impact state and federal budgets that rely on tobacco tax revenues, hurt small business, fail to reduce youth cigarette use even though youth cigarette use is currently at historic lows, and create a black market of unregulated menthol cigarettes that will put consumer in danger