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Sample size calculation The formula for a cross-sectional study was used to calculate the sample size for each selected village: where p is the prevalence of hypertension in the Chinese population 13 , is the margin of error (to estimate prevalence with a precision is equal to half of the prevalence of hypertension), and deff is the effect of design ( deff =2)

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(3) Menthol makes the sensation of smoking more harsh and bitter