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Over the past 20 years, PAHOs work on tobacco control has focused primarily on supporting countries in their efforts to adopt and implement the WHO Framework Convention on Tobacco Control (WHO FCTC), an international, legally binding treaty which promotes cost-effective tobacco control measures

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IL-4 and IL-13 are known to coincide with the switching of macrophages toward the M2-like phenotype and IL-10 is the typical cytokine released predominately by M2 macrophage