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Our results showed that the E-ACES could collect similar or slightly higher levels of low-molecular carbonyls (e.g., formaldehyde and acetaldehyde), but lower amounts of large-molecular compounds (e.g., benzaldehyde and hexaldehyde)

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The ubiquitin chains thus generated can interact with autophagy adaptors, recruiting LC3 (microtubuleassociated protein 1A/1Blight chain 3)positive autophagosomal membranes around the damaged mitochondrion, which is finally trafficked to the lysosome for degradation (Lazarou et al , 2015)

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