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Effects of Smoking on Male Fertility Sperm Health, Recovery Tips Effect of Smoking on Semen Quality Cigarette smoke contains harmful substances like nicotine, which can impair sperm production and function. 1. Reduced Sperm Count Smoking reduces the total number of sperm count. Effects of marijuana and tobacco on male fertility and their relationship to genetic variation of mitochondrial cytochrome C oxidase genes Scientific Reports Adverse Effects of Nicotine on Human Sperm Nuclear Proteins PMC
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