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Nicotine exposure can affect adolescent brain development, and flavored or high-concentration products have made e-cigarettes especially appealing to teens and young adults

In 2019, China issued the Notice on Further Protection of Minors from E-Cigarettes, urging e-commerce platforms, in particular, to remove e-cigarette products and withdraw related advertisements 33 , but businesses still used various methods such as renaming e-cigarettes to electronic atomizers to avoid regulation

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133 As aforementioned, prior to the enactment of the TCA, restrictions on the sale and distribution of tobacco products were primarily enforced at the state level, and compliance with state laws prohibiting tobacco sales to minors varied