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5 A 1980 study of the popular Potters brand found: smoking a herbal cigarette is associated with a significant fall in heart rate consistent with the systemic response to atropine-like alkaloids and a significant increase in peak expiratory flow rate consistent with the bronchodilator effect of reduced cholinergic activity. 6 However, it also concluded that although an asthma cigarette contains approximately 0.6 mg atropine-equivalent alkaloids, it is a crude preparation and, after smoking, the amount of active drug reaching the bronchial tree must be extremely variable and unpredictable. Additionally, the strength of toxins has been found to vary greatly (5:1) from plant to plant

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1997;156(11):S1