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At the beginning of week 10, reduce Nicotine Polacrilex Lozenge use even further, one every 4-8 hours

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Cotinine is the major metabolite of nicotine and further metabolised mainly to trans-3-hydroxy-cotinine, both quantifiable in body fluids and frequently applied biomarkers for recent tobacco exposure [4]

While nicotine is the chemical that keeps people addicted to smoking, there are over 60 known carcinogens in tobacco cigarettes, and thousands of other compounds that can affect things like nicotine uptake, and it is these chemicals that cause serious damage