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It affects almost every system in the body, leading to: Oral issues like stained teeth, gum infections, and bad breath Lung diseases such as COPD and chronic bronchitis Cardiovascular problems, including heart attacks and strokes Reduced reproductive health, affecting fertility in both men and women Increased risk of various cancers, especially oral and lung cancer Dangers of second-hand and third-hand smoke, which can harm non-smokers especially children and the elderly simply by being in the same room or touching contaminated surfaces

Without these strategies many more people would have chosen to stop smoking much earlier than they did and fewer would have taken up the habit.

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Once activated, they control immune responses by secreting specific effector cytokines: ILC1s, ILC2s, and ILC3s, respectively secrete interferon (IFN)-, IL-5, and IL-13, and IL-17A and IL-22 10