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Clinical examination Full skin examination assess for hyperextensibility of the skin and abnormal scarring The Beighton scale assess for hypermobility of a joint, in which a score of 5 or more indicates generalised joint hypermobility Investigations Skin biopsy for histology, fibroblast culture, and electron microscopy When suspecting kyphoscoliotic EDS, a urine sample is taken to measure the ratio of lysyl-pyridinoline to hydroxylysyl-pyridinoline cross-links Molecular genetic testing confirms the diagnosis, except in the case of hypermobile EDS, which has an unknown genetic basis and so is a clinical diagnosis which must meet all the clinical criteria

(ij) articles provided for in chapter 73 (except subheadings 7308.10, 7308.20, 7308.40 and 7308.90, subheadings 7315.81 through 7315.89, subheadings 7319.40, 7325.10, 7325.91, 7326.11 and 7326.19)