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3,4,9 Considering specific complications related to smoking, a study of data from 391,000 patients from the National Surgical Quality Improvement Program Database (NSQIP) showed that smoking status was independently associated with an increased risk of pneumonia (Odds Ratio 1.80, Confidence Interval 1.11, 2.92), unplanned intubation (OR 1.57, CI 1.10, 2.25) and requirement for ventilation for more than 48 hours (OR 1.73, CI 1.18, 2.53)

Incidentally, this strategy tends to decrease the sensitivity of gradual cessation, an effect that reinforces the significance of the observed differences

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