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The Dopamine Dilemma: ADHD and the Craving for Reward At the heart of ADHD lies a neurochemical imbalance , particularly involving dopamine , the brain's primary neurotransmitter responsible for pleasure, reward, and motivation

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However, nitrosated aqueous extract elicited mutagenic response in strains TA98 and TA100, while the aqueous ethanolic extract was highly mutagenic in strain TA 98.[] Micronucleus formation Micronucleus assay detects genotoxic effect of exposure to hazardous agents resulting in the formation of small membrane bound DNA fragments or micronuclei in the cytoplasm of interphase cells