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Given the cognitive effects of cannabis and the disruption of the endogenous cannabinoid system by tetrahydrocannabinol (THC), it may be that brain regions with high cannabinoid 1 (CB1) receptor density might be altered by cannabis. Utilizing functional MR imaging, the team compared connectivity in the brains of over 1,000 individuals as they completed a series of tasks related to memory, reward processing, emotion, language perception, motor skills, relational assessment, and theory of mind

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