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PEKN expression is decreased in COPD lung tissue, and PRKN knockout enhances airway wall thickening due to changes causing emphysema after CS exposure in COPD mice, compared with its effect in wild -type (WT) mice

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Researchers at the University of California, San Francisco, and University of Alabama at Birmingham knew tobacco smoking causes lung damage and leads to respiratory issues such as chronic obstructive pulmonary disease (COPD), but they wanted to be clear whether smoking marijuana, had similar effects