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[40] Tissue factor (TF)otherwise known as tissue platelet factor, or factor III, or thrombokinase, or CD 142is a protein found in endothelial tissue, platelets, and leucocytes, and is essential for the initiation of thrombus formation by zymogen prothrombin

And heres the thing: the mass addiction to cigarettes is not some natural phenomenon, but the result of deliberate and concerted efforts by a whole industry

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Defendants have collaborated with smugglers, encouraged smugglers, and sold cigarettes to smugglers, either directly or through intermediaries, while at the same time supporting the smugglers sales through the establishment and maintenance of so-called umbrella [cover] operations in the target jurisdictions. In 2015 British American Tobacco was accused of money laundering in South Africa