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Pain and hearing loss: The buildup of pus within the middle ear causes pain and dampens the vibrations of the eardrum (so there is usually temporary hearing loss during the infection)

Diacetyl is the chemical previously used in microwave popcorn to add a strong buttery flavor but found to cause irreversible lung damage and leading to the term popcorn lung disease. If vaped in high concentration, these chemicals can cause respiratory stress, lead to cellular damage and an increased risk of respiratory infections and chronic lung diseases

These factors ultimately determine the progression of injury, including excitotoxicity and neuronal loss

Women's Initiative for NonSmoking (WINS) VI: Reliability and validity of health and psychosocial measures in women smokers with cardiovascular disease