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This wasn't the case with boys, whose poly-drug use was instead predicted by the extent to which they perceived smoking to be prevalent in their larger age group not just among their friends

3 Moreover, alcohol consumption is directly correlated with smoking frequency, and high utilization of both substances exponentially increases the risk of developing adverse health effects like oral cancer

The Framingham study

Smoking can also cause tuberculosis, erectile dysfunction, facial clefts in infants, ectopic pregnancy, rheumatoid arthritis, inflammation, impaired immune function, and worsens the outlook for cancer patients and survivors