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Zuardi and colleagues first reported in 1995 in a patient that oral CBD (up to 1500 mg/day) led to improvements in Brief Psychiatric Rating Scale (BPRS) symptoms and a diazepam dose reduction in a 19-year-old female, which worsened with discontinuation of CBD [70]

Lancet Respir Med 4(2):116128 Leventhal AM, Strong DR, Kirkpatrick MG, Unger JB, Sussman S, Riggs NR et al (2015) Association of electronic cigarette use with initiation of combustible tobacco product smoking in early adolescence

This action conforms with WHO recommendations to ban the sale of cigarettes with characterizing flavors

The foremost tobacco control intervention to implement is monitoring the market, perceptions, and demographics targeted by flavored tobacco products stipulated by the WHO FCTC and the M in the MPOWER package [53]