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Nicotine can also promote endothelial dysfunction, inhibit cellular apoptosis and enhance angiogenesis, thereby raising concerns about its possible role in the pathophysiology of atherosclerosis and even cancer development.92,93 Interestingly, in another experiment, rats exposed to electronic cigarette refill liquid had better metabolic profiles, with decreased total cholesterol, low-density lipoprotein cholesterol and low-density lipoprotein:high-density lipoprotein ratio

A recent Cochrane-review [38] shows that the number of psychosocial interventions needed to treat for benefit is extraordinarily low, with approximately 71 interventions to prevent one preterm birth and 61 interventions to prevent one infant being born with low birth weight

Stenger, P