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Effects of Smokeless Tobacco Use on the Upper Gastrointestinal Tract Mucosa: Gross and Histopathological Changes PMC Can Cigarettes Cause Acid Reflux? Understanding the Risks Can smoking cause esophageal cancer? Roswell Park Comprehensive Cancer Center Buffalo, NY Acid reflux, or GERD, occurs when stomach acid flows back into the esophagus, leading to heartburn. Burning sensation after meals Regurgitation or sour taste Chest pain or discomfort
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