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Participants rated the low-nicotine cigarettes as less satisfying but also less dangerous than average-nicotine cigarettes, according to the researchers article, published in Nicotine and Tobacco Research January 2017

Also, overall, among individuals interesting in quitting cigarettes, those who receive smoking cessation interventions typically have better smoking abstinence rates and similar substance use outcomes over the short-term (i.e., 6 months or less)

Animal Data Pregnant rats and rabbits received varenicline succinate during organogenesis at oral doses up to 15 and 30 mg/kg/day, respectively