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This effect was greatest in the lung cells, but was also noticeable in the mouth, where every cell had an average of 23 mutations per pack year, as well as the bladder and the liver, where cells picked up 18 and six mutations respectively for each year of such excessive smoking

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It will create a stronger, global tobacco and NGP [new-generation products] business with direct access for our products across the most attractive markets in the world." Steve Clayton, fund manager at Hargreaves Lansdown, said the takeover was a "big move" for BAT, but made "a lot of sense"