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The authors would like to acknowledge support of the Clinical biomarker facility at SciLifeLab (Science for Life Laboratory, Uppsala University, SE-751 85 Uppsala Sweden) for providing assistance in protein analyses

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Another common trend is to see a cascade of laws over a predictable geography: Start in Europe, often Western European countries like Israel, Sweden, Germany Jump the pond to California Spread from California to rest of blue states Become federal law The Next Cigarette is Can we look at the early history of these regulated substances and forecast what toxins will be regulated in the future