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Supplementary Table 4 )

Oncology 85:216222

But they denied those hazards, hiring prominent researchers and lobbyists to wage public-awareness campaigns unpicking and calling into question the mounting evidence about links between smoking and cancer, heart disease, and early death

and PMN release large amounts of toxic oxygen free radicals and proteolytic enzymes, including elastase and collagenase, which act on lung elastin, mucin, basement membrane, and collagen fibers, leading to destruction of alveolar septa and interstitial fibrosis