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E-cig use in youth has also been associated with an increased risk for future addiction to other drugs and tobacco products.[ii] A 2018 study examined the association of depressive symptoms with the onset of e-cigarette use in adolescents

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A dose-response trend was also present with increasing ORs observed for higher levels of smoking (1-9 cigarettes daily: OR = 1.05, 95% CI: 0.95, 1.17