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Together with endogenously released ROS by inflammatory and lung structural cells as a result of tissue inflammation, the increased burden of oxidants in the lung contributes to the oxidative damage of lipids, proteins, and DNA in the lung

Most smokers would not have a problem with paying a bit beyond that, but when the government is making a profit (tax revenue minus healthcare cost due to smoking) of $1,771 per smoker already, which will rise to $2,902 with the tax hike, many will turn to the black market and thus no longer fund their own healthcare

Heat and light can dry out the tobacco and degrade its quality

Samir Gupta, a respirologist and an associate professor of medicine at the University of Toronto