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Volkow and her colleagues reviewed the literature on pathophysiological processes that may hasten aging and are particularly relevant to smoking, second hand smoke, drug use, and addictions.6 They focused on oxidative stress and cellular aging, inflammation in periphery and brain, decline in brain volume and function, and early onset of cardiac, cerebrovascular, kidney, and liver disease

While emphysema is most likely to develop in cigarette smokers, cigar and pipe smokers also are susceptible

Lau RY, Guo X

That's how you start the process." Steve Stauffer was a smoker for over 20 years, but quit immediately after being diagnosed with stage four lung cancer