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By January 1933, American Tobacco Company, noticing the booming market for inexpensive cigarettes, had reduced the wholesale price and returned to 10 cents per pack

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The section on Biomarkers offers an overview of in vitro and in vivo data on genotoxicity and cytotoxicity and a review of the literature on animal bioassays, in addition to general concepts of biomarkers of exposure, of biologically effective dose, and of potential harm, as an introduction to more detailed descriptions of biomarkers in subsequent chapters of this Surgeon Generals report