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4 Discussion Globally, cigarette smoking is the single most avoidable cause of illness and death, as well as the leading risk factor for COPD in Western societies ( Direct involvement of MoAM in the development of emphysema and tissue remodeling is supported by their molecular profile including the expression of elastolytic/matrix degrading and emphysema-associated markers

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FCTC Head Black explained that after many, many hours of debate, consensus this year just wasnt possible. The issue was postponed to COP12, scheduled for 2027

Using nicotine gum while quitting smoking: Nicotine replacement therapy (NRT) may blunt early weight gain for some people during treatment, especially when nicotine replacement is high enough (see a randomized controlled trial of nicotine gum and post-quit weight gain and MedlinePlus guidance on nicotine replacement therapy)