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While KD presents in children 5 years old or younger, MIS-C predominantly affects adolescents and children over 7 years old and is associated with diffuse cardiovascular involvement suggestive of a generalized immune-mediated disease following the onset of COVID-19 ( n = 129), had primarily respiratory system involvement (76.3%) with shortness of breath, pneumonia, and ARDS, indicating that their illnesses might have been primarily acute COVID-19 or a combination of acute COVID-19 and MIS-C

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"Statement from the Council of Chief Medical Officers of Health on the increasing rates of youth vaping in Canada"