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While NAC is generally considered safe and well-tolerated, some individuals should avoid it, including: People with asthma (NAC may trigger bronchospasm)

J Orthomol Psychiatry

Similar findings were reported in prospective clinical studies.68,69 A large multicenter RCT (n=194), however, found no significant differences with placebo.70 A meta-analysis of the above findings for a total of 480 patients showed a favorable effect on facial appearance.70 Multiple oral antioxidants and anti-inflammatory agents, such as vitamins A, C, D, and E, green tea polyphenols, niacinamide, and trace elements such as zinc may help mitigate signs of skin aging

Oxidative stress in plasma from patients with marfan syndrome is modulated by deodorized garlic preliminary findings