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A 2018 National Academies of Sciences, Engineering, and Medicine reportconcluded that there is substantial evidence that e-cigarette use increases risk of ever using combustible tobacco cigarettes among youth and young adults. A study by the University of Pittsburgh Schools of the Health Sciences found that young adults who use e-cigarettes are more than four times as likely to begin smoking tobacco cigarettes within 18 months as their peers who do not vape

However, it's not necessarily because the nail itself has turned yellow

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