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Half of these chemical compounds are produced by combustion alone, and are not present in raw tobacco leaf.[3] This cocktail of harmful chemicals found in tobacco smoke is directly tied to the substantial health impacts associated with cigarettes, with smoking directly contributing to 80%90% of all lung cancer deaths.[4] most of the studies analysing the effects of HTP have been conducted by manufacturers, but there is a growing body of independent research on HTP and more than 400 nonindustry studies have been published since 2024 In contrast, HTP use an electronic heating element to heat tobacco to approximately 350C.[5] This vaporises a number of compounds including nicotine, without causing the tobacco to burn