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Nicotine per se doesn't cause cancer, it is the poly cyclic aromatic hydrocarbons in the smoke (produced when a cigarette is lit) that is carcinogenic and stimulates other carcinogenic reactions," comments P K Julka, professor, department of radiology and oncology, All India Institute of Medical Sciences, Delhi

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Furthermore in an article on his website and co-authored by him, The Challenge of a Lifetime: A Look at the T206 Tobacco Set, theres no mention whatsoever of the Cobb variation, even in a table listing the 12 rarest cards in the set